Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017477 | 0.85 | LMNA (0.31) | LMNAMAPT | |
| SCHEMBL16371027 | 0.84 | LMNA (0.37) | LMNAMAPT | |
| SCHEMBL20234664 | 0.77 | NOS3 (0.33) | TDP1 | |
| SCHEMBL15543921 | 0.74 | LMNA (0.38) | LMNAMAPT | |
| SCHEMBL28045319 | 0.72 | ALDH1A1 (0.30) | — | |
| SCHEMBL2690837 | 0.71 | — | — | |
| SCHEMBL10211143 | 0.68 | MAPT (0.36) | MAPT | |
| SCHEMBL10274199 | 0.68 | MAPT (0.36) | MAPT | |
| SCHEMBL4106076 | 0.68 | GRIN2D (0.32) | — | |
| SCHEMBL21006006 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272293-B | 2-Amino-N-heteroaryl-nicotinamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2024-06-14 | — | — | CN | disclosed |