Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20234664 | 0.91 | NOS3 (0.33) | — | |
| SCHEMBL29250092 | 0.85 | LMNA (0.36) | LMNAMAPT | |
| SCHEMBL28045319 | 0.82 | ALDH1A1 (0.30) | — | |
| SCHEMBL16508872 | 0.76 | ACHE (0.35) | AR | |
| SCHEMBL16371027 | 0.72 | LMNA (0.37) | LMNAMAPT | |
| SCHEMBL29204778 | 0.72 | — | — | |
| SCHEMBL12356486 | 0.71 | KDM4E (0.45) | MAPT | |
| SCHEMBL19420074 | 0.71 | KDM4E (0.45) | MAPT | |
| SCHEMBL10211143 | 0.71 | MAPT (0.36) | MAPTAR | |
| SCHEMBL10274199 | 0.71 | MAPT (0.36) | MAPTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769554-A | Small molecule inhibitors of KRAS muteins | 大鹏药品工业株式会社 | 2024-03-26 | — | — | CN | disclosed |
| CN-115003673-B | Dihydropyrimidine compound, preparation method and application thereof | 上海维申医药有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-114555586-B | KRASG12C protein inhibitor and preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2023-06-23 | — | — | CN | disclosed |