Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 15/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 14/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3415876 | 0.88 | CDK4 (0.36) | ALDH1A1HCRTR2HCRTR1PDE4B | |
| SCHEMBL2925297 | 0.88 | CDK4 (0.36) | ALDH1A1HCRTR2HCRTR1PDE4B | |
| SCHEMBL2924242 | 0.86 | FABP4 (0.42) | PIK3CDMYCALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL2931912 | 0.86 | APOB (0.38) | PIK3CDALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL2925493 | 0.85 | HCRTR2 (0.37) | PIK3CDMYCHCRTR2HCRTR1 | |
| SCHEMBL2928147 | 0.85 | HCRTR1 (0.36) | PIK3CDALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL2931039 | 0.84 | HCRTR2 (0.39) | PIK3CDHCRTR2HCRTR1PDE4B | |
| SCHEMBL2928983 | 0.83 | GRM2 (0.40) | HCRTR2HCRTR1PDE4B | |
| SCHEMBL2932481 | 0.83 | GRM2 (0.40) | HCRTR2HCRTR1PDE4B | |
| SCHEMBL2926433 | 0.81 | MGLL (0.38) | PIK3CDALDH1A1HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079690-B1 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-09-15 | — | — | EP | disclosed |