Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 7/20 | 0.41 |
| ▸ | CES1 | P23141 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982035 | 0.90 | CES2 (0.50) | SMN1; SMN2TDP1CES2CES1ALDH1A1 | |
| SCHEMBL3312136 | 0.90 | CES2 (0.50) | SMN1; SMN2TDP1CES2CES1ALDH1A1 | |
| SCHEMBL30478610 | 0.90 | CES2 (0.50) | SMN1; SMN2TDP1CES2CES1ALDH1A1 | |
| SCHEMBL665971 | 0.90 | CES2 (0.50) | SMN1; SMN2TDP1CES2CES1ALDH1A1 | |
| SCHEMBL1978807 | 0.88 | ALDH1A1 (0.51) | SMN1; SMN2TDP1CES2CES1ALDH1A1 | |
| SCHEMBL13875404 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2TDP1CES2CES1ALDH1A1 | |
| SCHEMBL194429 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2TDP1CES2CES1ALDH1A1 | |
| Water SCHEMBL28017400 | 0.86 | ALDH1A1 (0.50) | SMN1; SMN2TDP1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL4738627 | 0.84 | CES2 (0.56) | SMN1; SMN2TDP1CES2CES1ALDH1A1 | |
| SCHEMBL14845439 | 0.82 | LMNA (0.54) | SMN1; SMN2TDP1CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118339216-A | Silsesquioxane derivative, curable composition, hard coating agent, cured product, hard coating, and substrate | 东亚合成株式会社 | 2024-07-12 | — | — | CN | disclosed |