Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 11/20 | 0.53 |
| ▸ | PARP11 | Q9NR21 | 10/20 | 0.53 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 5/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28724678 | 0.88 | PARP10 (0.53) | PARP10PARP11PARP1PDPK1GRM5 | |
| SCHEMBL30832847 | 0.80 | DRD2 (0.50) | MEN1KMT2A | |
| SCHEMBL31460423 | 0.80 | PRSS1 (0.44) | PARP10PARP11GRM5GSK3BMEN1 | |
| SCHEMBL8323443 | 0.78 | GRM5 (0.67) | PARP10PARP11PARP1PDPK1GRM5 | |
| SCHEMBL379341 | 0.78 | GRM5 (0.67) | PARP10PARP11PARP1PDPK1GRM5 | |
| SCHEMBL23160292 | 0.77 | PARP10 (0.47) | PARP10PARP11GRM5GSK3BMEN1 | |
| SCHEMBL29758907 | 0.77 | PARP10 (0.47) | PARP10PARP11GRM5GSK3BMEN1 | |
| SCHEMBL30421037 | 0.77 | PARP10 (0.57) | PARP10PARP11PARP1PDPK1GRM5 | |
| SCHEMBL28724505 | 0.76 | NTRK2 (0.46) | GSK3BMEN1KMT2A | |
| SCHEMBL6628767 | 0.76 | MAOA (0.54) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946093-A | Compounds useful as HPK1 inhibitors | 深圳福沃药业有限公司 | 2024-04-30 | — | — | CN | disclosed |