Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339505 | 0.75 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2NPSR1MAPT | |
| SCHEMBL2418749 | 0.73 | KDM4E (0.61) | RAB9ANPC1SMN1; SMN2POLBLMNA | |
| SCHEMBL28765148 | 0.72 | GAA (0.54) | RAB9ASMN1; SMN2L3MBTL1POLBNPSR1 | |
| SCHEMBL32660990 | 0.72 | GAA (0.59) | RAB9ANPC1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL206315 | 0.71 | PTPN11 (0.58) | SMN1; SMN2L3MBTL1LMNAHIF1AGAA | |
| SCHEMBL25263346 | 0.71 | MAPT (0.64) | SMN1; SMN2POLBMAPTLMNAHIF1A | |
| SCHEMBL8819152 | 0.69 | KDM4D (0.68) | L3MBTL1MAPTLMNAHIF1ATP53 | |
| SCHEMBL14305225 | 0.69 | ALDH1A1 (0.63) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL10473593 | 0.69 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2L3MBTL1POLB | |
| SCHEMBL18640729 | 0.68 | LMNA (0.56) | SMN1; SMN2L3MBTL1LMNAHIF1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116848107-A | Compounds and their use as PDE4 activators | 米罗尼德有限公司 | 2023-10-03 | — | — | CN | disclosed |