Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657647 | 0.80 | MEN1 (0.58) | ALDH1A1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL7004583 | 0.78 | MEN1 (0.61) | ALDH1A1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL5457779 | 0.73 | RAB9A (1.00) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL18177319 | 0.72 | PKM (1.00) | ALDH1A1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL8289584 | 0.72 | ALDH1A1 (0.88) | ALDH1A1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL21347432 | 0.70 | RAB9A (0.78) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2155229 | 0.69 | MAPK8 (0.70) | ALDH1A1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL29264398 | 0.69 | RAB9A (0.51) | ALDH1A1HPGDMEN1KMT2ARAB9A | |
| Niacinamide SCHEMBL5712652 | 0.68 | F7 (0.92) | ALDH1A1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL12768285 | 0.68 | RAB9A (0.61) | ALDH1A1HPGDMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002641-A2 | PROTEIN PHOSPHATASE INHIBITORS | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-01-03 | — | — | WO | disclosed |