Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19599427 | 0.85 | KMT2A (0.41) | ELANEALDH1A1KDM4EOPRK1KMT2A | |
| SCHEMBL17506427 | 0.77 | KMT2A (0.50) | ALDH1A1KDM4EOPRK1KMT2A | |
| SCHEMBL24917151 | 0.74 | RAB9A (0.34) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL8008974 | 0.72 | TDP1 (0.36) | KDM4E | |
| SCHEMBL21956901 | 0.70 | PDE4B (0.38) | OPRK1KMT2A | |
| SCHEMBL31525570 | 0.70 | ALDH1A1 (0.41) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL14884090 | 0.70 | CCR1 (0.33) | ALDH1A1KDM4E | |
| SCHEMBL12570324 | 0.69 | NOS3 (0.48) | ALDH1A1KDM4E | |
| SCHEMBL19542557 | 0.68 | AR (0.41) | ELANEALDH1A1KDM4EKMT2A | |
| SCHEMBL15745468 | 0.67 | GPR3 (0.39) | ELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135655-B | 1H-pyrazolo [4,3-d ] pyrimidine compounds as Toll-like receptor 7 (TLR 7) agonists | 百时美施贵宝公司 | 2024-07-02 | — | — | CN | disclosed |