Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3903181 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TOP2ABCHEACHETSHR | |
| Bromide SCHEMBL28065158 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TSHRL3MBTL1TP53POLB | |
| Hydrochloric Acid SCHEMBL5150273 | 0.86 | NPSR1 (0.60) | ALDH1A1BCHEACHETSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL10373049 | 0.85 | ACHE (0.44) | ALDH1A1TOP2ABCHEACHENPSR1 | |
| SCHEMBL13974631 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRTP53EPHX2NR1H4 | |
| SCHEMBL12905317 | 0.84 | ALDH1A1 (0.56) | ALDH1A1NPSR1L3MBTL1EPHX2NR1H4 | |
| SCHEMBL16433561 | 0.84 | ALDH1A1 (0.56) | ALDH1A1NPSR1L3MBTL1EPHX2NR1H4 | |
| Hydrochloric Acid SCHEMBL11637202 | 0.83 | ACHE (0.61) | ALDH1A1BCHEACHEKDM4E | |
| SCHEMBL3896216 | 0.83 | L3MBTL1 (0.61) | BCHEACHETSHRNPSR1L3MBTL1 | |
| SCHEMBL15142392 | 0.83 | LMNA (0.56) | ALDH1A1BCHEACHENPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118185047-A | Fluorescent metal-organic frame for visual detection of pesticide residues on fruits and vegetables and preparation method of spraying agent of fluorescent metal-organic frame | 江苏师范大学 | 2024-06-14 | — | — | CN | claimed |
| CN-118185047-A | Fluorescent metal-organic frame for visual detection of pesticide residues on fruits and vegetables and preparation method of spraying agent of fluorescent metal-organic frame | 江苏师范大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-118185047-A | Fluorescent metal-organic frame for visual detection of pesticide residues on fruits and vegetables and preparation method of spraying agent of fluorescent metal-organic frame | 江苏师范大学 | 2024-06-14 | — | — | CN | disclosed |