Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 9/20 | 0.55 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948256 | 1.00 | MMP9 (0.57) | MMP9TDP1MMP2ADAMTS4CA2 | |
| SCHEMBL8018411 | 0.88 | MMP9 (0.61) | MMP9TDP1MMP2ADAMTS4CA2 | |
| SCHEMBL617758 | 0.87 | MMP9 (0.60) | MMP9TDP1MMP2ADAMTS4CA2 | |
| SCHEMBL5481551 | 0.87 | MMP9 (0.60) | MMP9TDP1MMP2ADAMTS4CA2 | |
| SCHEMBL433896 | 0.85 | MMP9 (0.67) | MMP9TDP1MMP2ADAMTS4CA2 | |
| SCHEMBL561566 | 0.85 | MMP9 (0.67) | MMP9TDP1MMP2ADAMTS4CA2 | |
| SCHEMBL29961332 | 0.84 | MMP9 (0.63) | MMP9TDP1MMP2ADAMTS4CA2 | |
| SCHEMBL15213296 | 0.84 | MMP9 (0.63) | MMP9TDP1MMP2ADAMTS4CA2 | |
| SCHEMBL14519991 | 0.84 | MMP9 (0.63) | MMP9TDP1MMP2ADAMTS4CA2 | |
| SCHEMBL6331296 | 0.83 | MMP9 (0.61) | MMP9TDP1MMP2ADAMTS4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708740-B1 | PROTEASE INHIBITORS FOR THE TREATMENT OF DIGESTIVE PATHOLOGIES | RYTEK (FR) | 2010-09-29 | — | — | EP | claimed |
| JP-11228352-A | — | — | None | — | — | JP | disclosed |
| WO-2024151802-A2 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING ITCH | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2018055235-A1 | ISOXAZOLE-AMIDES FOR TREATING CARDIAC DISEASES | UNIVERSITY OF HELSINKI (FI) | 2018-03-29 | — | — | WO | disclosed |
| US-9841423-B2 | Methods for diagnosing and treating Helicobacter pylori infection | NATIONAL TSING HUA UNIVERSITY (TW) | 2017-12-12 | — | — | US | disclosed |
| US-20170082621-A1 | METHODS FOR DIAGNOSING AND TREATING HELICOBACTER PYLORI INFECTION | NATIONAL TSING HUA UNIVERSITY (TW) | 2017-03-23 | — | — | US | disclosed |
| WO-2016032319-A1 | PROTEIN QUANTITATION WITH MASS SPECTROMETRY. | ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) | 2016-03-03 | — | — | WO | disclosed |
| US-8673312-B2 | Method for one-step purification of recombinant Helicobacter pylori neutrophil-activating protein | NATIONAL TSING HUA UNIVERSITY (TW) | 2014-03-18 | — | — | US | disclosed |
| US-20130190482-A1 | METHOD FOR ONE-STEP PURIFICATION OF RECOMBINANT HELICOBACTER PYLORI NEUTROPHIL-ACTIVATING PROTEIN | NATIONAL TSING HUA UNIVERSITY (TW) | 2013-07-25 | — | — | US | disclosed |
| EP-0739983-B1 | Gene encoding lacto-n-biosidase | TAKARA BIO INC (JP) | 2009-12-30 | — | — | EP | disclosed |
| EP-1161452-B1 | COVALENTLY BRIDGED INSULIN DIMERS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-15 | — | — | EP | disclosed |
| EP-1588163-A2 | KINASES AND GPCRS INVOLVED IN APOPTOSIS | Eirx Therapeutics Ltd (IE) | 2005-10-26 | — | — | EP | disclosed |
| US-20050019746-A1 | Apoptosis-related kinase/GPCRs | EIRX THERAPEUTICS LIMITED | 2005-01-27 | — | — | US | disclosed |
| US-20040219616-A1 | Apoptosis-related kinase/GPCRs | EIRX THERAPEUTICS LIMITED | 2004-11-04 | — | — | US | disclosed |
| WO-2004065959-A2 | KINASES AND GPCRS INVOLVED IN APOPTOSIS | EIRX THERAPEUTICS LIMITED (IE) | 2004-08-05 | — | — | WO | disclosed |
| US-5985637-A | DNA WHICH ENCODES AN ENZYME IMPORTANT IN CARBOHYDRATE ANALYSIS AND REARRANGEMENTS; FOR INDUSTRIAL-SCALE PRODUCTION OF ENZYME BY RECOMBINANT TECHNOLOGY | TAKARA SHUZO CO., LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| JP-H11228352-A | HAIR TONIC AND HAIR TREATMENT | KANEBO LTD | 1999-08-24 | — | — | JP | disclosed |
| US-5908772-A | A DNA SEQUENCE ENCODING A FUNCTIONALLY ACTIVE POLYPEPTIDE WHICH CATLYZES THE HYDROLYSIS OF LACTO-N-BIOSIDE BONDS; INDUSTRIAL SCALE PRODUCTION | TAKARA SHUZO CO., LTD. (JP) | 1999-06-01 | — | — | US | disclosed |
| EP-0769550-A2 | Gene encoding endo-beta-n-acetyl glucosaminidase A | TAKARA SHUZO CO. LTD. (JP) | 1997-04-23 | — | — | EP | disclosed |
| EP-0739983-A2 | Gene encoding lacto-n-biosidase | TAKARA SHUZO CO. LTD. (JP) | 1996-10-30 | — | — | EP | disclosed |