SCHEMBL617758

SCHEMBL617758

Cc1ccc(S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)C(Cl)C(=O)C(Cl)C(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MMP9 P14780 9/20 0.60
▸ TDP1 Q9NUW8 1/20 0.59
▸ MMP2 P08253 9/20 0.59
▸ ADAMTS4 O75173 1/20 0.59
▸ CTSL P07711 1/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ ADAMTS5 Q9UNA0 1/20 0.56
▸ MAPT P10636 1/20 0.56
▸ POLB P06746 1/20 0.56
▸ CA2 P00918 1/20 0.55
▸ CA7 P43166 1/20 0.55
▸ GAA P10253 1/20 0.53
▸ MMP1 P03956 1/20 0.53
▸ MMP3 P08254 1/20 0.53
▸ MMP7 P09237 1/20 0.53
▸ MMP13 P45452 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5481551 1.00 MMP9 (0.60) MMP9TDP1MMP2ADAMTS4CTSL
SCHEMBL8018411 0.91 MMP9 (0.61) MMP9TDP1MMP2ADAMTS4CTSL
SCHEMBL14519991 0.87 MMP9 (0.63) MMP9TDP1MMP2ADAMTS4CTSL
SCHEMBL15213296 0.87 MMP9 (0.63) MMP9TDP1MMP2ADAMTS4CTSL
SCHEMBL4948256 0.87 MMP9 (0.57) MMP9TDP1MMP2ADAMTS4CTSL
SCHEMBL2926667 0.87 MMP9 (0.57) MMP9TDP1MMP2ADAMTS4CTSL
Chloromethane SCHEMBL7649372 0.86 MMP2 (0.75) MMP9TDP1MMP2ADAMTS4CTSL
SCHEMBL628639 0.86 MMP9 (0.64) MMP9TDP1MMP2ADAMTS4CTSL
SCHEMBL20601786 0.86 MMP9 (0.64) MMP9TDP1MMP2ADAMTS4CTSL
SCHEMBL628640 0.86 MMP9 (0.64) MMP9TDP1MMP2ADAMTS4CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11228352-A — — None — — JP disclosed
EP-4000905-B1 PUNCTURE SEALANT SUMITOMO RUBBER IND (JP) 2025-04-09 — — EP disclosed
WO-2024151802-A2 METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING ITCH PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-07-18 — — WO disclosed
CN-118272323-A Influenza B virus mutants and uses thereof 复尔健有限公司 2024-07-02 — — CN disclosed
CN-117693359-A Broadly reactive viral antigens as immunogens, compositions and methods of use 乔治亚大学研究基金会股份有限公司 2024-03-12 — — CN disclosed
CN-117561449-A Biomarkers for determining immune oncologic response 维恩生物科学公司 2024-02-13 — — CN disclosed
CN-110573613-B Influenza B virus mutants and uses thereof 复尔健有限公司 2024-01-09 — — CN disclosed
US-11732113-B2 Puncture sealant SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-08-22 — — US disclosed
CN-116456895-A Biomarkers for diagnosing non-alcoholic steatohepatitis (NASH) or hepatocellular carcinoma (HCC) 韦恩生物科技股份公司 2023-07-18 — — CN disclosed
EP-4000905-A1 PUNCTURE SEALANT Sumitomo Rubber Industries, Ltd. (JP) 2022-05-25 — — EP disclosed
EP-0434605-B1 Novel process for the production of unfused protein in E. coli CIBA GEIGY AG (CH) 1996-09-11 — — EP disclosed
WO-1995035366-A1 ANIMAL MODEL FOR ALZHEIMER'S DISEASE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1995-12-28 — — WO disclosed
EP-0537155-A1 PURIFIED RAP GAPs, RAP GAP SEQUENCES, AND USES THEREOF CHIRON CORPORATION (US) 1993-04-21 — — EP disclosed
WO-1993000926-A1 TREATMENT OF PERIODONTAL DISEASE WITH PROTEASE INHIBITORS CHILDREN'S MEDICAL CENTER CORPORATION (US) 1993-01-21 — — WO disclosed
WO-1991015582-A2 PURIFIED RAP GAPs, RAP GAP SEQUENCES, AND USES THEREOF CETUS CORPORATION (US) 1991-10-17 — — WO disclosed
EP-0434605-A2 Novel process for the production of unfused protein in E. coli CIBA-GEIGY AG (CH) 1991-06-26 — — EP disclosed
US-4906571-A Cell surface modification using a novel glycoproteinase of pasteurella haemolytica UNIVERSITY OF GUELPH (CA) 1990-03-06 — — US disclosed
US-4861865-A Novel antithrombin peptide WASHINGTON UNIVERSITY (US) 1989-08-29 — — US disclosed
EP-0182906-A1 HUMAN LEUKOCYTE ELASTASE INHIBITORS PREPARED FROM PYOGENIC BACTERIA AND METHODS FOR THEIR PURIFICATION CORTECH, INC. (US) 1986-06-04 — — EP disclosed
WO-1986000077-A1 HUMAN LEUKOCYTE ELASTASE INHIBITORS PREPARED FROM PYOGENIC BACTERIA AND METHODS FOR THEIR PURIFICATION CORTECH, INC. (US) 1986-01-03 — — WO disclosed
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