Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 9/20 | 0.60 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | MMP7 | P09237 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481551 | 0.91 | MMP9 (0.60) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL617758 | 0.91 | MMP9 (0.60) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL14519991 | 0.88 | MMP9 (0.63) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL15213296 | 0.88 | MMP9 (0.63) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL4948256 | 0.88 | MMP9 (0.57) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL2926667 | 0.88 | MMP9 (0.57) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| Chloromethane SCHEMBL7649372 | 0.87 | MMP2 (0.75) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL628639 | 0.87 | MMP9 (0.64) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL20601786 | 0.87 | MMP9 (0.64) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL628640 | 0.87 | MMP9 (0.64) | MMP9TDP1MMP2ADAMTS4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087530-A | Process for preparing β-amino-α-hydroxy acid derivatives | KANEKA CORPORATION (JP) | 2000-07-11 | — | — | US | disclosed |
| US-6020518-A | Process for preparing β-amino-α-hydroxy acid derivatives | KANEKA CORPORATION (JP) | 2000-02-01 | — | — | US | disclosed |