Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6849472 | 0.83 | L3MBTL1 (0.36) | ALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL28948615 | 0.79 | PTGER1 (0.41) | — | |
| SCHEMBL6852914 | 0.79 | — | — | |
| SCHEMBL3644184 | 0.78 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL4336208 | 0.75 | ALDH1A1 (0.34) | ALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL3361154 | 0.72 | MAPT (0.38) | ALDH1A1HTT | |
| SCHEMBL8622377 | 0.72 | — | — | |
| SCHEMBL2338138 | 0.71 | TSHR (0.32) | HSD17B10 | |
| SCHEMBL8377967 | 0.71 | — | — | |
| SCHEMBL28712291 | 0.70 | KMT2A (0.34) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111087315-A | Synthetic method of eltrombopag intermediate and synthetic method of eltrombopag | 武汉武药科技有限公司 | 2020-05-01 | — | — | CN | claimed |
| EP-1294378-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2004-01-28 | — | — | EP | claimed |
| EP-1294378-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-03-26 | — | — | EP | claimed |
| WO-2001089457-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-29 | — | — | WO | claimed |
| CN-111087315-A | Synthetic method of eltrombopag intermediate and synthetic method of eltrombopag | 武汉武药科技有限公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-111087315-A | Synthetic method of eltrombopag intermediate and synthetic method of eltrombopag | 武汉武药科技有限公司 | 2020-05-01 | — | — | CN | disclosed |