Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29273408 | 0.91 | TTR (0.45) | RORCSLC22A12TTRRARG | |
| SCHEMBL30933433 | 0.87 | MAPK14 (0.43) | RORC | |
| SCHEMBL23355447 | 0.87 | MAPK14 (0.43) | RORC | |
| SCHEMBL23355436 | 0.78 | JAK1 (0.39) | CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL29273417 | 0.74 | NOTUM (0.36) | RORCSLC22A12 | |
| SCHEMBL29273412 | 0.69 | ALDH1A1 (0.38) | SLC22A12 | |
| SCHEMBL9907631 | 0.69 | HTR5A (0.51) | RORCSLC22A12TTR | |
| SCHEMBL23355481 | 0.69 | PIK3C2B (0.42) | RORCCYP3A4CYP1A2CYP2C19 | |
| SCHEMBL30933431 | 0.69 | PIK3C2B (0.42) | RORCCYP3A4CYP1A2CYP2C19 | |
| SCHEMBL952060 | 0.69 | SCN3A (0.39) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996788-B | Anthelmintic heterocyclic compounds | 勃林格殷格翰动物保健美国公司 | 2024-07-16 | — | — | CN | disclosed |