Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ATXN2 | Q99700 | 6/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723005 | 0.82 | ENPP2 (0.43) | NAAACTSKCARM1PRMT6GRM2 | |
| SCHEMBL29277450 | 0.81 | CARM1 (0.50) | NAAACTSKCARM1PRMT6GRM2 | |
| SCHEMBL20708874 | 0.80 | NAAA (0.38) | NAAACTSKCARM1PRMT6 | |
| SCHEMBL21722847 | 0.79 | NAAA (0.44) | NAAACTSKCARM1PRMT6ENPP2 | |
| SCHEMBL22462930 | 0.78 | LIPE (0.46) | GRM2ENPP2ATXN2 | |
| SCHEMBL25325640 | 0.76 | SLC6A2 (0.43) | NAAACTSKCARM1PRMT6ENPP2 | |
| SCHEMBL29277461 | 0.75 | IDO1 (0.49) | NAAA | |
| SCHEMBL29277432 | 0.75 | IDO1 (0.50) | NAAACARM1PRMT6 | |
| SCHEMBL25326239 | 0.71 | GPR119 (0.51) | ENPP2ATXN2 | |
| SCHEMBL17769042 | 0.71 | GPR3 (0.40) | ENPP2CHRM5FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |