SCHEMBL292785

SCHEMBL292785

CCC1CNCC(CC)N1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
CCR5 P51681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14085933 1.00 MGAM (0.33) MGAMGAASIMGAM2CCR5
SCHEMBL5750982 1.00 MGAM (0.33) MGAMGAASIMGAM2CCR5
SCHEMBL13127200 0.87
Acetic Acid SCHEMBL34474209 0.85 CHRNB2 (0.35) MGAMGAASIMGAM2
SCHEMBL18436931 0.84
SCHEMBL15488925 0.84
SCHEMBL293407 0.83 GLB1 (0.39) MGAMGAASIMGAM2
SCHEMBL16661382 0.82
SCHEMBL25774805 0.82 ALDH1A1 (0.32)
SCHEMBL292784 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092138-A1 BLOCKED POLYISOCYANATE COMPOSITION, CURABLE RESIN COMPOSITION COMPRISING THE COMPOSITION, AND CURED PRODUCT KOEI CHEMICAL COMPANY, LIMITED (JP) 2026-04-02 US disclosed
EP-4703326-A1 METHOD FOR RECOVERING ALKALI METAL SALT AND APPARATUS FOR RECOVERING ALKALI METAL SALT Toray Industries, Inc. (JP) 2026-03-04 EP disclosed
EP-4628199-A1 COMPOSITE SEMIPERMEABLE MEMBRANE, COMPOSITE SEMIPERMEABLE MEMBRANE ELEMENT, AND FILTER DEVICE Toray Industries, Inc. (JP) 2025-10-08 EP disclosed
EP-4628609-A1 METHOD FOR RECOVERING ALKALI METAL SALT AND APPARATUS FOR RECOVERING ALKALI METAL SALT Toray Industries, Inc. (JP) 2025-10-08 EP disclosed
WO-2025070624-A1 METHOD AND DEVICE FOR RECOVERING ALKALI METAL IONS AND HYDROXIDE IONS 東レ株式会社 2025-04-03 WO disclosed
WO-2024225409-A1 METHOD FOR RECOVERING ALKALI METAL SALT AND APPARATUS FOR RECOVERING ALKALI METAL SALT 東レ株式会社 2024-10-31 WO disclosed
US-20240247088-A1 DISPERSANT FOR POWER STORAGE DEVICE POSITIVE ELECTRODE KAO CORPORATION (JP) 2024-07-25 US disclosed
WO-2024117238-A1 COMPOSITE SEMIPERMEABLE MEMBRANE, COMPOSITE SEMIPERMEABLE MEMBRANE ELEMENT, AND FILTER DEVICE 東レ株式会社 2024-06-06 WO disclosed
WO-2024117236-A1 METHOD FOR RECOVERING ALKALI METAL SALT AND APPARATUS FOR RECOVERING ALKALI METAL SALT 東レ株式会社 2024-06-06 WO disclosed
EP-4336596-A1 DISPERSANT FOR POWER STORAGE DEVICE POSITIVE ELECTRODE Kao Corporation (JP) 2024-03-13 EP disclosed
EP-2287162-A1 Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders Otsuka Pharmaceutical Co., Ltd. (JP) 2011-02-23 EP disclosed
EP-2287161-A1 Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders Otsuka Pharmaceutical Co., Limited (JP) 2011-02-23 EP disclosed
EP-2284169-A1 Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of CNS disorders Otsuka Pharmaceutical Co., Limited (JP) 2011-02-16 EP disclosed
US-20100317568-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2010-12-16 US disclosed
US-20100197703-A1 N-SULFONYL THIAZOLYLPIPERAZINE DERIVATIVES AND RELATED N-SULFONYL HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES NV REMYND (BE) 2010-08-05 US disclosed
US-20090264404-A1 Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-10-22 US disclosed
US-7414057-B2 Piperazine urea derivatives as melanocortin-4 receptor agonists MERCK & CO., INC. (US) 2008-08-19 US disclosed
US-7414057-B2 Piperazine urea derivatives as melanocortin-4 receptor agonists MERCK & CO., INC. (US) 2008-08-19 US disclosed
US-4837324-A Process for the reaction of piperazine, and derivatives thereof, with glyoxal, and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1989-06-06 US disclosed
US-4761476-A Compounds formed by the reaction of piperazine, and derivatives thereof, with glyoxal, and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1988-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317568-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS MGAM 2749/4885GAA 223/4885SI 3674/4885
US-20100197703-A1 N-SULFONYL THIAZOLYLPIPERAZINE DERIVATIVES AND RELATED N-SULFONYL HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES SMN1; SMN2, HTT, SNCA MGAM 3724/4885GAA 110/4885SI 1100/4885
US-20260092138-A1 BLOCKED POLYISOCYANATE COMPOSITION, CURABLE RESIN COMPOSITION COMPRISING THE COMPOSITION, AND CURED PRODUCT RER1, RPP30, REV1 MGAM 2823/4885GAA 3726/4885SI 2401/4885
US-20090264404-A1 Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders GRIN2C, GRIN2B, PMP22 MGAM 4151/4885GAA 3355/4885SI 4578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.