Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600115 | 0.75 | MAOB (0.44) | MAOBSIGMAR1 | |
| SCHEMBL29054876 | 0.72 | KCNJ1 (0.46) | CYP1A2 | |
| SCHEMBL23044930 | 0.70 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL15954401 | 0.70 | MAOB (0.47) | MAOB | |
| SCHEMBL28042762 | 0.69 | HSD11B1 (0.42) | HSP90AA1 | |
| SCHEMBL13526966 | 0.69 | MAOB (0.57) | MAOBGFER | |
| SCHEMBL30483417 | 0.68 | MAOB (0.48) | MAOBGRM2GRM3ESRRGGFER | |
| SCHEMBL5031225 | 0.68 | LMNA (0.59) | SIGMAR1 | |
| SCHEMBL5480690 | 0.68 | FAAH (0.44) | SIGMAR1 | |
| SCHEMBL27648358 | 0.67 | KDM4E (0.33) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580592-A | Compounds for targeting bruton's tyrosine kinase degradation | 渤健马萨诸塞州股份有限公司 | 2024-02-20 | — | — | CN | disclosed |