Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178234 | 0.87 | CRBN (0.46) | — | |
| SCHEMBL2178285 | 0.82 | FAAH (0.44) | FAAHTMEM97MEN1KMT2ALMNA | |
| SCHEMBL2176256 | 0.82 | HTR1A (0.47) | FAAHNAAATMEM97ALDH1A1KCNH2 | |
| Hydrochloric Acid SCHEMBL2178562 | 0.81 | FAAH (0.43) | FAAHTMEM97MEN1KMT2ALMNA | |
| SCHEMBL5477755 | 0.78 | FAAH (0.57) | FAAHMEN1KMT2APOLBKCNH2 | |
| SCHEMBL28042762 | 0.76 | HSD11B1 (0.42) | MEN1KMT2AKDM4ELMNAPOLB | |
| SCHEMBL1581970 | 0.75 | GRIN2D (0.47) | FAAH | |
| SCHEMBL5475896 | 0.75 | SIGMAR1 (0.58) | FAAHMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1581171 | 0.73 | OPRK1 (0.48) | FAAHKDM4EALDH1A1MGLL | |
| SCHEMBL29054876 | 0.71 | KCNJ1 (0.46) | LMNAALDH1A1MAPTKCNH2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | claimed |
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | disclosed |