Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30262334 | 1.00 | PKM (0.40) | PKMMEP1BKMT2AALDH1A1KDM4E | |
| SCHEMBL38652331 | 0.84 | PKM (0.44) | PKMKMT2ATDP1NLRP3L3MBTL1 | |
| SCHEMBL1477877 | 0.84 | PKM (0.44) | PKMKMT2ATDP1NLRP3L3MBTL1 | |
| SCHEMBL28416113 | 0.82 | ALDH1A1 (0.42) | PKMKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL31063021 | 0.82 | NLRP3 (0.47) | PKMKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL24780447 | 0.81 | MEP1B (0.43) | MEP1BKDM4E | |
| SCHEMBL30262386 | 0.81 | MEP1B (0.43) | MEP1BKDM4E | |
| SCHEMBL28980523 | 0.80 | P2RX7 (0.43) | PKMKDM4E | |
| SCHEMBL31287934 | 0.80 | MEP1B (0.43) | MEP1B | |
| SCHEMBL20346349 | 0.79 | KMT2A (0.42) | PKMMEP1BKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858875-A | Hydroxy-and (halo) alkoxy-substituted tetrahydrofurans as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-04-09 | — | — | CN | disclosed |