Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927815 | 0.85 | RAB9A (0.42) | RAB9ATDP1KMT2AALDH1A1ATM | |
| SCHEMBL2929023 | 0.75 | RAB9A (0.38) | RAB9ATDP1KMT2AALDH1A1NPC1 | |
| SCHEMBL2928341 | 0.74 | ALDH1A1 (0.42) | RAB9ATDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL6151831 | 0.71 | RAB9A (0.61) | RAB9ATDP1KMT2AALDH1A1ATM | |
| SCHEMBL6645015 | 0.71 | RAB9A (0.61) | RAB9ATDP1KMT2AALDH1A1ATM | |
| SCHEMBL8716892 | 0.71 | RAB9A (0.61) | RAB9ATDP1KMT2AALDH1A1ATM | |
| SCHEMBL20919972 | 0.69 | ALDH1A1 (0.54) | RAB9AKMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL7166054 | 0.69 | CNR1 (0.47) | RAB9ATDP1KMT2AALDH1A1NPC1 | |
| SCHEMBL28696515 | 0.68 | RAB9A (0.44) | RAB9ATDP1KMT2AATMNPC1 | |
| Bicarbonate SCHEMBL30096531 | 0.68 | ALDH1A1 (0.64) | RAB9ATDP1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499620-B1 | PROCESS FOR PREPARING 6-ALKYLIDENE PENEM DERIVATIVES | WYETH CORP (US) | 2010-01-27 | — | — | EP | disclosed |
| EP-1499620-A1 | PROCESS FOR PREPARING 6-ALKYLIDENE PENEM DERIVATIVES | Wyeth (US) | 2005-01-26 | — | — | EP | disclosed |
| US-20040132708-A1 | Process for preparing 6-alkylidene penem derivatives | WYETH | 2004-07-08 | — | — | US | disclosed |
| US-20040053913-A1 | Process for preparing 6-alkylidene penem derivatives | WYETH | 2004-03-18 | — | — | US | disclosed |
| WO-2003093277-A1 | PROCESS FOR PREPARING 6-ALKYLIDENE PENEM DERIVATIVES | WYETH (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132708-A1 | Process for preparing 6-alkylidene penem derivatives | PGM2, BPGM, MRPL21 | RAB9A 1712/4885TDP1 4462/4885KMT2A 3127/4885 |
| US-20040053913-A1 | Process for preparing 6-alkylidene penem derivatives | PGM2, BPGM, MRPL21 | RAB9A 1712/4885TDP1 4462/4885KMT2A 3127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.