Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15586787 | 0.77 | MAOA (0.39) | PTGDR2HSD11B1ALDH1A1KDM4EHPGD | |
| SCHEMBL29285182 | 0.76 | CCNA2 (0.37) | PTGDR2HSD11B1MAOA | |
| SCHEMBL20536581 | 0.75 | ABL1 (0.40) | PTGDR2PPARGPPARDALDH1A1KDM4E | |
| SCHEMBL28952200 | 0.74 | L3MBTL1 (0.46) | HSD11B1MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL29711925 | 0.74 | L3MBTL1 (0.46) | HSD11B1MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL20536419 | 0.72 | ABL1 (0.41) | PTGDR2PPARGPPARDALDH1A1KDM4E | |
| SCHEMBL29285155 | 0.72 | ALDH1A1 (0.37) | PTGDR2HSD11B1MAPTALDH1A1KDM4E | |
| SCHEMBL30877369 | 0.72 | ALDH1A1 (0.37) | PTGDR2HSD11B1MAPTALDH1A1KDM4E | |
| SCHEMBL20502546 | 0.70 | PTGDR2 (0.43) | PTGDR2PPARGPPARDMAPTALDH1A1 | |
| SCHEMBL29285186 | 0.70 | CREBBP (0.34) | PTGDR2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |