Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | LATS1 | O95835 | 9/20 | 0.38 |
| ▸ | LATS2 | Q9NRM7 | 8/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27109643 | 0.87 | LATS1 (0.43) | ACHELATS1LATS2DHODHKDM4C | |
| SCHEMBL15515002 | 0.78 | CYP1A2 (0.58) | ACHELATS1LATS2CLK1CDK5 | |
| SCHEMBL28042218 | 0.73 | ALDH1A1 (0.62) | ACHELMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL21297879 | 0.72 | LATS1 (0.41) | ACHELATS1LATS2DHODHKDM4C | |
| SCHEMBL20669767 | 0.71 | PDE10A (0.66) | LATS1DHODH | |
| SCHEMBL27109644 | 0.71 | DHODH (0.43) | ACHECLK1CYP1A2DHODH | |
| SCHEMBL13169638 | 0.70 | GPR3 (0.64) | LATS1LATS2CLK1CYP1A2DHODH | |
| SCHEMBL250853 | 0.70 | ACHE (0.42) | ACHELATS1LATS2CLK1LMNA | |
| SCHEMBL11365189 | 0.70 | KDM4E (0.41) | CLK1CDK5CDK5R1LMNACYP1A2 | |
| SCHEMBL11374086 | 0.70 | KDM4E (0.41) | CLK1CDK5CDK5R1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490527-A | Bicyclic derivatives | 瑞士伊兰科动物保健有限公司 | 2021-10-08 | — | — | CN | disclosed |