SCHEMBL29290551

SCHEMBL29290551

CCCCCC(=O)C1(Cc2ccccc2)C=CC=CC1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MMP2 P08253 2/20 0.39
MMP9 P14780 2/20 0.39
MMP8 P22894 2/20 0.39
MMP13 P45452 2/20 0.39
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
HPGD P15428 1/20 0.37
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 2/20 0.36
TSHR P16473 2/20 0.36
MAPK1 P28482 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
FAAH O00519 1/20 0.36
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29060724 0.71 MAOA (0.33) HPGDALDH1A1
SCHEMBL28517989 0.70 AKR1B1 (0.31) MEN1KMT2AALDH1A1TSHRTDP1
Hexanoate SCHEMBL27672924 0.69 AKR1B1 (0.61) EPHX2MEN1KMT2AALDH1A1TSHR
Isopropylbenzene SCHEMBL30175415 0.68 OPRM1 (0.37) MEN1KMT2AHPGDALDH1A1L3MBTL1
SCHEMBL30128591 0.68 HSD11B1 (0.41) EPHX2MEN1KMT2AALDH1A1MAPK1
Stearic Acid SCHEMBL28201794 0.68 GPR84 (0.63) EPHX2MEN1KMT2AALDH1A1TSHR
Hexanoate SCHEMBL28265608 0.65 AKR1B1 (0.55) EPHX2MEN1KMT2AALDH1A1TSHR
Ethylbenzene SCHEMBL31086323 0.64 HDAC11 (0.59) MEN1KMT2ACES2CES1ALDH1A1
Decanoic Acid SCHEMBL6362431 0.64 GPR84 (0.61) EPHX2MEN1KMT2AALDH1A1TSHR
Octanoic Acid SCHEMBL11522036 0.64 MEN1 (0.64) MEN1KMT2AHPGDALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-A Reversible thermal discoloration composition, reversible thermal discoloration microcapsule pigment encapsulating the reversible thermal discoloration composition, and writing instrument using the reversible thermal discoloration microcapsule pigment 百乐墨水株式会社 2021-11-12 CN disclosed