Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933140 | 0.83 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL2498882 | 0.78 | POLB (0.39) | CRHR1 | |
| SCHEMBL2929947 | 0.78 | CYP1A2 (0.34) | CRHR1 | |
| SCHEMBL2495462 | 0.78 | KDM4E (0.38) | CRHR1 | |
| SCHEMBL2495432 | 0.75 | POLB (0.40) | CRHR1 | |
| SCHEMBL2931328 | 0.74 | PIK3CG (0.38) | — | |
| SCHEMBL2493432 | 0.74 | CYP1A2 (0.37) | CRHR1 | |
| SCHEMBL2932900 | 0.72 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL2930712 | 0.71 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL2498943 | 0.70 | BRD4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094709-B1 | THIAZOLE PYRAZOLOPYRIMIDINES AS CRF1 RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2010-09-15 | — | — | EP | disclosed |