Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13342413 | 1.00 | FFAR4 (0.38) | FFAR4PTGS1PTGS2HTTALDH1A1 | |
| SCHEMBL28131083 | 0.84 | FFAR4 (0.47) | FFAR4PTGS1PTGS2HTTALDH1A1 | |
| SCHEMBL26676087 | 0.82 | PTGS2 (0.32) | PTGS1PTGS2RAPGEF4 | |
| SCHEMBL26432134 | 0.79 | FFAR4 (0.36) | FFAR4PTGS1PTGS2HTTALDH1A1 | |
| SCHEMBL15787572 | 0.78 | MAOA (0.41) | PTGS1PTGS2SKP2 | |
| SCHEMBL20708489 | 0.77 | SIGMAR1 (0.44) | HTTSKP2NPC1RAB9AHPGD | |
| SCHEMBL6793126 | 0.77 | RIPK1 (0.38) | PTGS2HTTNPC1RAB9AHPGD | |
| SCHEMBL23655537 | 0.76 | FFAR4 (0.37) | FFAR4PTGS1PTGS2HTTALDH1A1 | |
| SCHEMBL24595109 | 0.76 | PTGS1 (0.33) | PTGS1PTGS2 | |
| SCHEMBL18553018 | 0.76 | PTGS1 (0.40) | PTGS1PTGS2HTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |