Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 11/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 11/20 | 0.63 |
| ▸ | PDE4A | P27815 | 7/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.50 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10595977 | 0.90 | PDE3B (0.64) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7417981 | 0.82 | PDE3B (0.57) | PDE3BPDE3APDE4APDE4BPDE4C | |
| Prinoxodan SCHEMBL122042 | 0.80 | PDE3B (0.55) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10835125 | 0.80 | PDE3B (0.59) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10744506 | 0.79 | PDE3B (0.54) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7483850 | 0.78 | PDE3B (0.70) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10596133 | 0.77 | PDE3B (0.61) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10353452 | 0.77 | SMN1; SMN2 (0.81) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7342078 | 0.76 | PDE3B (0.53) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9590230 | 0.76 | PDE3B (0.59) | PDE3BPDE3APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155798-B1 | PYRIDAZONE INOTROPIC AGENTS | ELI LILLY AND COMPANY (US) | 1989-02-08 | — | — | EP | claimed |
| US-4591591-A | FOR TREATING HEART FAILURE | ELI LILLY AND COMPANY (US) | 1986-05-27 | — | — | US | claimed |
| EP-0155798-A1 | Pyridazone inotropic agents | ELI LILLY AND COMPANY (US) | 1985-09-25 | — | — | EP | claimed |
| US-20260077139-A1 | SPACER DEVICE WITH FLOW RATE SPIROMETER | AEROVU TECHNOLOGIES, INC. (US) | 2026-03-19 | — | — | US | disclosed |
| US-12514993-B2 | Spacer device with flow rate spirometer | AEROVU TECHNOLOGIES, INC. (US) | 2026-01-06 | — | — | US | disclosed |
| US-20250339374-A1 | BONDED MICROPARTICULATES PREPARATION AND APPLICATIONS THEREOF | VENKOR CORP (US) | 2025-11-06 | — | — | US | disclosed |
| WO-2023234935-A1 | BONDED MICROPARTICULATES PREPARATION AND APPLICATIONS THEREOF | VENKOR CORPORATION (US) | 2023-12-07 | — | — | WO | disclosed |
| US-11590084-B2 | Microcapsules for controlled delivery of an active pharmaceutical ingredient | BIELSKI ROMAN (US) | 2023-02-28 | — | — | US | disclosed |
| EP-3194033-B1 | SPACER DEVICE WITH FLOW RATE SPIROMETER | AEROVU TECH INC (US) | 2022-05-04 | — | — | EP | disclosed |
| US-20190125687-A1 | Microcapsules for Controlled Delivery of an Active Pharmaceutical Ingredient | BIELSKI ROMAN (US) | 2019-05-02 | — | — | US | disclosed |
| US-9919116-B2 | Inhaler | VECTURA DELIVERY DEVICES LIMITED (GB) | 2018-03-20 | — | — | US | disclosed |
| EP-0155798-B1 | PYRIDAZONE INOTROPIC AGENTS | ELI LILLY AND COMPANY (US) | 1989-02-08 | — | — | EP | disclosed |
| US-4647564-A | PYRIDAZINONE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-03-03 | — | — | US | disclosed |
| US-4591591-A | FOR TREATING HEART FAILURE | ELI LILLY AND COMPANY (US) | 1986-05-27 | — | — | US | disclosed |
| EP-0161918-A2 | Indoline and 2-indolinone derivatives | ELI LILLY AND COMPANY (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0155798-A1 | Pyridazone inotropic agents | ELI LILLY AND COMPANY (US) | 1985-09-25 | — | — | EP | disclosed |
| US-4474785-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | BASF AKTIENGESELLSCHAFT (DE) | 1984-10-02 | — | — | US | disclosed |
| EP-0068310-B1 | 2-ARYL-3,4-DIAZA-BICYCLO(4.N.0)ALKEN-(2)-ONES-(5), PROCESS FOR THEIR PREPARATION, AND MEDICINES CONTAINING THESE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1984-08-08 | — | — | EP | disclosed |
| EP-0068310-A1 | 2-Aryl-3,4-diaza-bicyclo(4.n.0)alken-(2)-ones-(5), process for their preparation, and medicines containing these compounds | BASF Aktiengesellschaft (DE) | 1983-01-05 | — | — | EP | disclosed |
| US-4258185-A | HYPOTENSIVE, ANTITHROMBOTIC AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1981-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190125687-A1 | Microcapsules for Controlled Delivery of an Active Pharmaceutical Ingredient | PUF60, SRM, SMS | PDE3B 2656/4885PDE3A 2277/4885PDE4A 3265/4885 |
| US-20260077139-A1 | SPACER DEVICE WITH FLOW RATE SPIROMETER | TMCO1, CFTR, CYSLTR2 | PDE3B 1302/4885PDE3A 878/4885PDE4A 1992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.