Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25355009 | 0.84 | PLA2G10 (0.40) | ALDH1A1MEN1KMT2AMAPTPLA2G10 | |
| SCHEMBL18173577 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AMAPTPLA2G10 | |
| SCHEMBL8634516 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AMAPTPLA2G10 | |
| SCHEMBL14306830 | 0.83 | SMN1; SMN2 (0.40) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL16900147 | 0.81 | WNT1 (0.38) | PLA2G10PLA2G5HTR4HPGD | |
| SCHEMBL29042818 | 0.80 | KDM4E (0.44) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2925781 | 0.80 | KDM4E (0.44) | ALDH1A1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL2925780 | 0.79 | KDM4E (0.43) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4026767 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2APLA2G10PLA2G5 | |
| SCHEMBL4180063 | 0.78 | CTSK (0.43) | ALDH1A1MEN1KMT2APLA2G10PLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148029-A2 | ORGANIC COMPOUNDS AS NLRP3 INHIBITORS | KODIAK SCIENCES INC. (US) | 2024-07-11 | — | — | WO | disclosed |