Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1351011 | 0.84 | LATS1 (0.37) | CYP2C19CYP1A2CYP2C9HTTSMN1; SMN2 | |
| SCHEMBL202837 | 0.82 | BTK (0.38) | GHSRMEN1KMT2A | |
| SCHEMBL76966 | 0.79 | BTK (0.38) | GHSRMEN1ALDH1A1KMT2A | |
| SCHEMBL583634 | 0.78 | KMT2A (0.38) | CYP2C19CYP1A2CYP2C9HTTSMN1; SMN2 | |
| SCHEMBL8981350 | 0.78 | FAAH (0.39) | GHSRMEN1KMT2A | |
| SCHEMBL8980908 | 0.78 | FAAH (0.39) | GHSRMEN1KMT2A | |
| SCHEMBL496169 | 0.78 | FAAH (0.39) | GHSRMEN1KMT2A | |
| SCHEMBL1012064 | 0.78 | FAAH (0.39) | GHSRMEN1KMT2A | |
| SCHEMBL550992 | 0.78 | FAAH (0.39) | GHSRMEN1KMT2A | |
| SCHEMBL4675685 | 0.78 | CYP1A2 (0.39) | CYP2C19CYP1A2CYP2C9HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217610-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | Achaogen, Inc. (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009067692-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2009-05-28 | — | — | WO | disclosed |