SCHEMBL202837

SCHEMBL202837

CC(C)(C)OC(=O)NC1(C(=O)O)CCC1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
MAPK1 P28482 1/20 0.37
GHSR Q92847 1/20 0.34
GAA P10253 3/20 0.34
CTSL P07711 1/20 0.34
FAAH O00519 1/20 0.34
APLNR P35414 1/20 0.33
EPHX1 P07099 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76966 0.96 BTK (0.38) BTKKMT2AMEN1MAPK1GHSR
SCHEMBL1012064 0.95 FAAH (0.39) BTKKMT2AMEN1MAPK1GHSR
SCHEMBL8980908 0.95 FAAH (0.39) BTKKMT2AMEN1MAPK1GHSR
SCHEMBL8981350 0.95 FAAH (0.39) BTKKMT2AMEN1MAPK1GHSR
SCHEMBL496169 0.95 FAAH (0.39) BTKKMT2AMEN1MAPK1GHSR
SCHEMBL550992 0.95 FAAH (0.39) BTKKMT2AMEN1MAPK1GHSR
SCHEMBL142219 0.92 MEN1 (0.39) BTKKMT2AMEN1MAPK1GHSR
SCHEMBL5103879 0.86 BTK (0.35) BTKKMT2AMEN1MAPK1GHSR
SCHEMBL2085827 0.86 CXCR5 (0.40) BTKKMT2AMEN1MAPK1GHSR
SCHEMBL18482795 0.86 GAA (0.36) BTKKMT2AMEN1MAPK1GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534652-A Preparation method of apatamide 黄冈人福药业有限责任公司 2024-02-09 CN claimed
CN-114478627-A Allylation monophosphine ligand and preparation method thereof 湖北大学 2022-05-13 CN claimed
CN-112876507-A Trisubstituted olefin tertiary phosphine compound and preparation method thereof 湖北大学 2021-06-01 CN claimed
CN-109851635-B Novel alkylated monophosphine ligand and simple preparation method thereof 湖北大学 2021-03-16 CN claimed
CN-112250709-A Synthesis method of ortho-aryl substituted tertiary phosphine compound 湖北大学 2021-01-22 CN claimed
CN-111592567-A Synthesis method of bidentate phosphine ene ligand 湖北大学 2020-08-28 CN claimed
CN-109851635-A A kind of new alkylation monophosphorus ligand and its simple preparation method 湖北大学 2019-06-07 CN claimed
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD (US) 2026-04-02 US disclosed
EP-4702033-A1 DESMURAMYLPEPTIDE DIACIDS AS NOD2 AGONISTS AND USE THEREOF Imhotex Limited (GB) 2026-03-04 EP disclosed
EP-4695237-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS F. Hoffmann-La Roche AG (CH) 2026-02-18 EP disclosed
US-20260041673-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD (US) 2026-02-12 US disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-4674484-A2 THIENOPYRROLE COMPOUNDS Gilead Sciences, Inc. (US) 2026-01-07 EP disclosed
US-20030220375-A1 N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives MERCK SHARP & DOHME LLC 2003-11-27 US disclosed
WO-2003065789-A2 N-BIPHENYLMETHYL AMINOCYCLOALKANECARBOXAMIDE DERIVATIVES MERCK & CO., INC. (US) 2003-08-14 WO disclosed
WO-2003066577-A1 N-BIPHENYLMETHYL AMINOCYCLOALKANECARBOXAMIDE DERIVATIVES WITH A SUBSTIITUENT ON THE METHYL USEFUL AS BRADYKININ ANTAGONISTS MERCK & CO., INC. (US) 2003-08-14 WO disclosed
EP-1304329-A2 Pyridonecarboxylic acid derivatives and their use as antibacterial agents DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-04-23 EP disclosed
US-5849757-A Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1998-12-15 US disclosed
EP-0807630-A1 HETEROCYCLIC COMPOUNDS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1997-11-19 EP disclosed
US-5543414-A VIRICIDES SYNTEX (USA) INC. (US) 1996-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE IL6ST, GFRA3, GFRA1 BTK 3487/4885KMT2A 3288/4885MEN1 3255/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 BTK 2244/4885KMT2A 1052/4885MEN1 4664/4885
US-20030220375-A1 N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives BDKRB1, BDKRB2, CNR2 BTK 1416/4885KMT2A 771/4885MEN1 2380/4885
US-20260041673-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE GFRA3, IL6ST, GFRA1 BTK 3608/4885KMT2A 3363/4885MEN1 3290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.