SCHEMBL496169

SCHEMBL496169

CC(C)(C)OC(=O)NC1(C(=O)O)CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 9/20 0.39
BTK Q06187 1/20 0.37
GAA P10253 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPK1 P28482 1/20 0.36
EPHX1 P07099 1/20 0.36
P2RX7 Q99572 1/20 0.35
TRPV1 Q8NER1 6/20 0.35
MAPT P10636 1/20 0.34
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
CTSS P25774 1/20 0.34
GHSR Q92847 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1012064 1.00 FAAH (0.39) FAAHBTKGAAMEN1KMT2A
SCHEMBL8981350 1.00 FAAH (0.39) FAAHBTKGAAMEN1KMT2A
SCHEMBL8980908 1.00 FAAH (0.39) FAAHBTKGAAMEN1KMT2A
SCHEMBL550992 1.00 FAAH (0.39) FAAHBTKGAAMEN1KMT2A
SCHEMBL76966 0.98 BTK (0.38) FAAHBTKGAAMEN1KMT2A
SCHEMBL202837 0.95 BTK (0.38) FAAHBTKGAAMEN1KMT2A
SCHEMBL142219 0.91 MEN1 (0.39) BTKGAAMEN1KMT2AMAPK1
SCHEMBL27646197 0.87 GAA (0.37) FAAHBTKGAAMEN1KMT2A
SCHEMBL15116645 0.86 GAA (0.36) FAAHBTKGAAMEN1KMT2A
SCHEMBL2789711 0.85 GHSR (0.37) FAAHBTKGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824545-B Preparation method of trans-4-N-Boc-aminocyclohexane carboxylic acid 泰州精英化成医药科技有限公司 2021-02-26 CN claimed
CN-105085296-B The method that one kind prepares trans 4 (t-butoxycarbonyl amino) cyclohexanecarboxylic acid intermediate isomerization 常州齐晖药业有限公司 2017-08-08 CN claimed
WO-2013033520-A1 A METHOD FOR REGULATING SKIN PIGMENTATION THE GENERAL HOSPITAL CORPORATION (US) 2013-03-07 WO claimed
US-7276496-B2 Cyclic malonamides as inhibitors of Aβ protein protection BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2007-10-02 US claimed
US-12583825-B2 Benzo[h]quinazolin-4-amine and thieno[3,2-h]quinazolin-4-amine derivatives for the treatment of cancer Redona Therapeutics, Inc. (US) 2026-03-24 US disclosed
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists DOMAIN THERAPEUTICS (FR) 2026-01-20 US disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-4568959-A1 BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2025-06-18 EP disclosed
CN-119930740-A Dipeptide compound, chimeric molecule based on dipeptide compound and application of dipeptide compound 西南交通大学 2025-05-06 CN disclosed
WO-2025090774-A1 CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE SEAGEN INC. (US) 2025-05-01 WO disclosed
US-20250114313-A1 OLIGO-BENZAMIDE ANALOGS AND THEIR USE IN CANCER TREATMENT BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-10 US disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
US-5175146-A Improved potency; storage stability; nonhydrolyzing; osteoporosis; Paget's disease; hypocalcemic VICAL, INC. (US) 1992-12-29 US disclosed
EP-0513974-A1 Novel benzo-fused lactams that promote the release of growth hormone MERCK & CO. INC. (US) 1992-11-19 EP disclosed
CN-1066070-A Promote the new benzo-fused lactams that tethelin discharges MERCK & CO INC (US) 1992-11-11 CN disclosed
WO-1992016524-A1 BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE MERCK & CO., INC. (US) 1992-10-01 WO disclosed
EP-0480969-A1 AMINO ACID ANALOG CCK ANTAGONISTS ABBOTT LABORATORIES (US) 1992-04-22 EP disclosed
WO-1991000725-A2 AMINO ACID ANALOG CCK ANTAGONISTS ABBOTT LABORATORIES (US) 1991-01-24 WO disclosed
EP-0310918-A2 Peptide-like amino-acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1989-04-12 EP disclosed
US-4297489-A CEPHALOSPORINS BRISTOL-MYERS COMPANY (US) 1981-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists PTGER1, PTGER4, PTGER3 FAAH 279/4885BTK 3996/4885GAA 4880/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 FAAH 3992/4885BTK 2244/4885GAA 2026/4885
US-20250114313-A1 OLIGO-BENZAMIDE ANALOGS AND THEIR USE IN CANCER TREATMENT GAA, LIPA, LIPE FAAH 620/4885BTK 1337/4885GAA 1/4885
US-12583825-B2 Benzo[h]quinazolin-4-amine and thieno[3,2-h]quinazolin-4-amine derivatives for the treatment of cancer H1-3, RB1, H1-2 FAAH 1895/4885BTK 54/4885GAA 4135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.