Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763236 | 0.80 | MAOA (0.55) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL544963 | 0.80 | MAOA (0.55) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL1375648 | 0.80 | MAOA (0.50) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL31180999 | 0.75 | MAOA (0.49) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL3709991 | 0.74 | KDM4E (0.48) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL30641650 | 0.74 | KDM4E (0.64) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL30593474 | 0.74 | KDM4E (0.64) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| SCHEMBL654368 | 0.74 | KDM4E (0.64) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| Xanthone SCHEMBL41161 | 0.73 | MAOA (1.00) | MAOAKDM4EALDH1A1GLACYP3A4 | |
| Xanthone SCHEMBL29358061 | 0.73 | MAOA (1.00) | MAOAKDM4EALDH1A1GLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501398-B2 | Luminescence assay using macrocyclic lanthanide (III) complexes | UNIVERSITY OF DURHAM (GB) | 2013-08-06 | — | — | US | disclosed |
| EP-2041571-B1 | LUMINESCENCE ASSAY USING MACROCYCLIC LANTHANIDE (III) COMPLEXES | UNIV DURHAM (GB) | 2010-09-15 | — | — | EP | disclosed |
| US-20100055665-A1 | LUMINESCENCE ASSAY USING MACROCYCLIC LANTHANIDE (III) COMPLEXES | UNIVERSITY OF DURHAM (GB) | 2010-03-04 | — | — | US | disclosed |