Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAOA | P21397 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986282 | 0.88 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL15696821 | 0.88 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL30593474 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1MAOASMN1; SMN2HPGD | |
| SCHEMBL654368 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1MAOASMN1; SMN2HPGD | |
| SCHEMBL30641650 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1MAOASMN1; SMN2HPGD | |
| SCHEMBL14676605 | 0.75 | CASP3 (0.54) | KDM4EALDH1A1MAOASMN1; SMN2HPGD | |
| SCHEMBL544963 | 0.74 | MAOA (0.55) | KDM4EALDH1A1MAOASMN1; SMN2HPGD | |
| SCHEMBL2763236 | 0.74 | MAOA (0.55) | KDM4EALDH1A1MAOASMN1; SMN2HPGD | |
| SCHEMBL2930770 | 0.74 | MAOA (0.55) | KDM4EALDH1A1MAOASMN1; SMN2HPGD | |
| SCHEMBL7845838 | 0.74 | KMT2A (0.44) | KDM4EALDH1A1MAOASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010084090-A1 | PYRIDYL-AZA(THIO)XANTHONE SENSITIZER COMPRISING LANTHANIDE(III) ION COMPLEXING COMPOUNDS, THEIR LUMINESCENT LANTHANIDE (III) ION COMPLEXES AND USE THEREOF AS FLUORESCENT LABELS. | CIS BIO INTERNATIONAL (FR) | 2010-07-29 | — | — | WO | disclosed |