Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2930770 | 0.80 | MAOA (0.55) | MAOAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL2763236 | 0.76 | MAOA (0.55) | MAOAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL544963 | 0.76 | MAOA (0.55) | MAOAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL3709991 | 0.71 | KDM4E (0.48) | MAOAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL654368 | 0.70 | KDM4E (0.64) | MAOAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL30593474 | 0.70 | KDM4E (0.64) | MAOAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL30641650 | 0.70 | KDM4E (0.64) | MAOAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL8711806 | 0.70 | MAOA (0.60) | MAOAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL4696277 | 0.70 | MAOA (0.90) | MAOAKDM4EALDH1A1HPGDGLA | |
| Xanthone SCHEMBL29398266 | 0.70 | MAOA (1.00) | MAOAKDM4EALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391610-B1 | LUMINESCENT LANTHANIDE COMPLEXES | UNIV DURHAM (GB) | 2016-10-26 | — | — | EP | disclosed |
| US-9448225-B2 | Responsive luminescent lathanide complexes | UNIVERSITY OF DURHAM (GB) | 2016-09-20 | — | — | US | disclosed |
| US-20140179015-A1 | RESPONSIVE LUMINESCENT LATHANIDE COMPLEXES | UNIVERSITY OF DURHAM (GB) | 2014-06-26 | — | — | US | disclosed |
| US-8628978-B2 | Responsive luminescent lanthanide complexes | UNIVERSITY OF DURHAM (GB) | 2014-01-14 | — | — | US | disclosed |
| US-8501398-B2 | Luminescence assay using macrocyclic lanthanide (III) complexes | UNIVERSITY OF DURHAM (GB) | 2013-08-06 | — | — | US | disclosed |
| US-20110287558-A1 | RESPONSIVE LUMINESCENT LANTHANIDE COMPLEXES | UNIVERSITY OF DURHAM (GB) | 2011-11-24 | — | — | US | disclosed |
| EP-2041571-B1 | LUMINESCENCE ASSAY USING MACROCYCLIC LANTHANIDE (III) COMPLEXES | UNIV DURHAM (GB) | 2010-09-15 | — | — | EP | disclosed |
| US-20100055665-A1 | LUMINESCENCE ASSAY USING MACROCYCLIC LANTHANIDE (III) COMPLEXES | UNIVERSITY OF DURHAM (GB) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179015-A1 | RESPONSIVE LUMINESCENT LATHANIDE COMPLEXES | GLRX3, SUCNR1, SDHA | MAOA 4342/4885KDM4E 532/4885ALDH1A1 511/4885 |
| US-20110287558-A1 | RESPONSIVE LUMINESCENT LANTHANIDE COMPLEXES | GLRX3, SDHA, SUCNR1 | MAOA 3792/4885KDM4E 561/4885ALDH1A1 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.