SCHEMBL29308481

SCHEMBL29308481

CCCCC(=O)NCC(=O)NC(CCC(N)=O)C(=O)NCC(=O)NCC(=O)NCC(=O)NC(C)C(=O)NCC(=O)N1CCCC1C(=O)NCC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 2/20 0.44
▸ NAA50 Q9GZZ1 1/20 0.39
▸ FAP Q12884 2/20 0.39
▸ NMUR2 Q9GZQ4 3/20 0.38
▸ NMUR1 Q9HB89 3/20 0.38
▸ ACE P12821 3/20 0.36
▸ ACE2 Q9BYF1 3/20 0.36
▸ P2RY12 Q9H244 3/20 0.36
▸ EPHA2 P29317 1/20 0.35
▸ F2 P00734 1/20 0.35
▸ RAMP3 O60896 1/20 0.35
▸ CALCR P30988 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29308716 0.98 APLNR (0.44) APLNRNAA50FAPNMUR2NMUR1
SCHEMBL29308468 0.94 APLNR (0.43) APLNRNAA50FAPNMUR2NMUR1
SCHEMBL26387434 0.93 FAP (0.40) APLNRNAA50FAPNMUR2NMUR1
SCHEMBL29308704 0.91 FAP (0.40) APLNRNAA50FAPNMUR2NMUR1
SCHEMBL22019479 0.89 NAA50 (0.39) APLNRNAA50FAPNMUR2NMUR1
SCHEMBL22018362 0.87 FAP (0.38) APLNRNAA50FAPNMUR2NMUR1
SCHEMBL23871517 0.86 FAP (0.38) APLNRNAA50FAPNMUR2NMUR1
SCHEMBL29308547 0.85 APLNR (0.39) APLNRNAA50FAPNMUR2NMUR1
SCHEMBL26391856 0.84 APLNR (0.38) APLNRNAA50FAPNMUR2NMUR1
SCHEMBL23191159 0.82 APLNR (0.49) APLNRNAA50FAPF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient YUYU PHARMA, INC. (KR) 2024-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient VIP, IAPP, NGLY1 APLNR 334/4885NAA50 4530/4885FAP 530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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