SCHEMBL29308704

SCHEMBL29308704

CC(N)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NCC(=O)NCC(=O)NCC(=O)NC(C)C(=O)NCC(=O)N1CCCC1C(=O)NCC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FAP Q12884 2/20 0.40
▸ NAA50 Q9GZZ1 1/20 0.39
▸ APLNR P35414 1/20 0.39
▸ OPRM1 P35372 1/20 0.35
▸ OPRD1 P41143 1/20 0.35
▸ CALCRL Q16602 2/20 0.35
▸ GLO1 Q04760 1/20 0.35
▸ NMUR2 Q9GZQ4 1/20 0.34
▸ NMUR1 Q9HB89 1/20 0.34
▸ RAMP3 O60896 4/20 0.34
▸ CALCR P30988 4/20 0.34
▸ KEAP1 Q14145 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26387434 0.93 FAP (0.40) FAPNAA50APLNROPRM1OPRD1
SCHEMBL22019479 0.91 NAA50 (0.39) FAPNAA50APLNROPRM1OPRD1
SCHEMBL29308481 0.91 APLNR (0.44) FAPNAA50APLNRNMUR2NMUR1
SCHEMBL29308468 0.90 APLNR (0.43) FAPNAA50APLNRNMUR2NMUR1
SCHEMBL22018362 0.89 FAP (0.38) FAPNAA50APLNRCALCRLNMUR2
SCHEMBL29308716 0.89 APLNR (0.44) FAPNAA50APLNRCALCRLNMUR2
SCHEMBL23871517 0.88 FAP (0.38) FAPNAA50APLNRCALCRLNMUR2
SCHEMBL26391856 0.86 APLNR (0.38) FAPNAA50APLNRCALCRLNMUR2
SCHEMBL29565172 0.84 GRB2 (0.43) FAPNAA50OPRM1OPRD1GLO1
SCHEMBL29308497 0.83 FAP (0.36) FAPNAA50APLNRCALCRLNMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient YUYU PHARMA, INC. (KR) 2024-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient VIP, IAPP, NGLY1 FAP 530/4885NAA50 4530/4885APLNR 334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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