Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 4/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15536148 | 0.82 | AURKB (0.64) | MAPTMEN1KMT2ANAMPTALDH1A1 | |
| SCHEMBL23019288 | 0.82 | ROCK2 (0.63) | ROCK2MAPTMEN1HTTKMT2A | |
| SCHEMBL3243101 | 0.81 | ROCK2 (1.00) | ROCK2MAPTMEN1HTTKMT2A | |
| SCHEMBL3246062 | 0.79 | ROCK2 (0.70) | ROCK2MAPTMEN1KMT2AHIF1A | |
| SCHEMBL23019558 | 0.76 | RORC (0.61) | ROCK2NAMPTRORCALDH1A1 | |
| SCHEMBL19349408 | 0.72 | MEN1 (0.53) | ROCK2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4637492 | 0.72 | KMT2A (0.61) | ROCK2MAPTMEN1HTTKMT2A | |
| SCHEMBL20290927 | 0.70 | LRRK2 (0.58) | MAPTMEN1KMT2ANAMPT | |
| SCHEMBL20379328 | 0.70 | NAMPT (0.76) | MAPTMEN1HTTKMT2ANAMPT | |
| SCHEMBL21286084 | 0.70 | WNT1 (0.64) | MAPTMEN1KMT2ANAMPTRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |