Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 15/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29315949 | 0.72 | LRRK2 (0.48) | AURKALRRK2SYK | |
| SCHEMBL29315109 | 0.70 | PRKCQ (0.40) | AURKALRRK2 | |
| SCHEMBL29313569 | 0.69 | TNK2 (0.48) | — | |
| SCHEMBL13523666 | 0.69 | KDM4E (0.41) | AURKALRRK2IDH1ADORA2AADORA1 | |
| SCHEMBL29314449 | 0.69 | CHEK1 (0.49) | LRRK2SYK | |
| SCHEMBL29313573 | 0.69 | LRRK2 (0.47) | LRRK2 | |
| SCHEMBL29313773 | 0.69 | CCNA2 (0.46) | AURKALRRK2SYK | |
| SCHEMBL20920627 | 0.69 | LRRK2 (0.46) | LRRK2IDH1 | |
| SCHEMBL5764208 | 0.68 | KDM4E (0.48) | AURKALRRK2IDH1SYK | |
| SCHEMBL25598891 | 0.67 | CSNK1A1 (0.42) | AURKALRRK2IDH1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |