Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313569 | 0.80 | TNK2 (0.48) | JAK2CHEK1 | |
| SCHEMBL29314449 | 0.74 | CHEK1 (0.49) | LRRK2PRKCQCHEK1 | |
| SCHEMBL29315949 | 0.74 | LRRK2 (0.48) | LRRK2PRKCQ | |
| SCHEMBL29313579 | 0.74 | KAT2B (0.42) | LRRK2PRKCQ | |
| SCHEMBL29313773 | 0.71 | CCNA2 (0.46) | LRRK2PRKCQ | |
| SCHEMBL29313719 | 0.69 | AURKA (0.38) | LRRK2 | |
| SCHEMBL29313606 | 0.69 | PTK2 (0.40) | LRRK2PRKCQ | |
| SCHEMBL23019347 | 0.68 | PRKCQ (0.41) | LRRK2PRKCQ | |
| SCHEMBL29315063 | 0.68 | LRRK2 (0.35) | LRRK2PRKCQ | |
| SCHEMBL19476565 | 0.68 | MERTK (0.62) | PRKCQCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |