Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 11/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | ROS1 | P08922 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313573 | 0.80 | LRRK2 (0.47) | CHEK1JAK2 | |
| SCHEMBL29314449 | 0.78 | CHEK1 (0.49) | CHEK1MAP3K8MAPK1 | |
| SCHEMBL4766348 | 0.77 | CCNA2 (0.59) | TNK2CHEK1JAK2ABL1LCK | |
| SCHEMBL29313579 | 0.77 | KAT2B (0.42) | ABL1SRCMAP3K8 | |
| SCHEMBL3892231 | 0.74 | KDM4E (0.45) | TNK2ALDH1A1KDM4EGAANPC1 | |
| SCHEMBL22079965 | 0.73 | CHEK1 (0.53) | CHEK1ALDH1A1KDM4EGAANPC1 | |
| SCHEMBL4770586 | 0.73 | CCNA2 (0.59) | TNK2CHEK1JAK2ABL1LCK | |
| SCHEMBL12523516 | 0.72 | ALDH1A1 (0.55) | TNK2ALDH1A1KDM4EGAANPC1 | |
| SCHEMBL23019347 | 0.72 | PRKCQ (0.41) | — | |
| SCHEMBL29313773 | 0.71 | CCNA2 (0.46) | ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |