Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.56 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.56 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.44 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313615 | 0.85 | VNN1 (0.47) | PTK2PTK2BPGK1ALDH1A1MEN1 | |
| SCHEMBL29313552 | 0.85 | PTK2 (0.43) | PTK2PTK2BHDAC3HDAC1HDAC2 | |
| SCHEMBL29313606 | 0.84 | PTK2 (0.40) | PTK2PTK2BPGK1KDM4EGAA | |
| SCHEMBL29313621 | 0.84 | PTK2 (0.41) | PTK2PTK2BALDH1A1MEN1KMT2A | |
| SCHEMBL18419810 | 0.81 | APP (0.48) | PTK2PTK2BPGK1LMNAKDM4E | |
| SCHEMBL29313542 | 0.79 | ALDH1A1 (0.54) | MAP3K8PGK1LMNATSHRHTT | |
| SCHEMBL9849594 | 0.78 | LMNA (0.49) | PTK2PTK2BKCNA5PGK1LMNA | |
| SCHEMBL29315070 | 0.77 | MAP3K8 (0.45) | PTK2PTK2BMAP3K8KDM4EALDH1A1 | |
| SCHEMBL9849512 | 0.76 | MAOA (0.51) | KCNA5PGK1LMNATSHRHTT | |
| SCHEMBL29315097 | 0.75 | MAP3K8 (0.43) | PTK2PTK2BMAP3K8IGF1RSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |