Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.47 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21011556 | 0.76 | TSHR (0.48) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL23037497 | 0.75 | PTGES (0.47) | TLR8TLR7ACHEHTT | |
| SCHEMBL30539858 | 0.75 | PTGES (0.47) | TLR8TLR7ACHEHTT | |
| SCHEMBL1008890 | 0.74 | TLR7 (0.49) | TLR8TLR7DCPSADORA3KDM4E | |
| SCHEMBL29526654 | 0.74 | ADORA3 (0.47) | TLR8TLR7DCPSADORA3KDM4E | |
| SCHEMBL1233223 | 0.74 | ADORA3 (0.47) | TLR8TLR7DCPSADORA3KDM4E | |
| SCHEMBL30539814 | 0.74 | DCPS (0.48) | TLR8TLR7DCPSADORA3KDM4E | |
| SCHEMBL29314505 | 0.74 | DCPS (0.48) | TLR8TLR7DCPSADORA3KDM4E | |
| SCHEMBL1234454 | 0.74 | TLR7 (0.49) | TLR8TLR7DCPSADORA3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5572086 | 0.73 | ADORA3 (0.46) | TLR8TLR7DCPSADORA3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2024-07-16 | — | — | US | disclosed |
| US-12037344-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | NLRP3, NLRP1, PYCARD | TLR8 210/4885TLR7 236/4885DCPS 3366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.