Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22109191 | 0.90 | MET (0.38) | METNQO2DYRK1AJAK2TGFBR1 | |
| SCHEMBL22109646 | 0.79 | MET (0.40) | METDYRK1A | |
| SCHEMBL29317548 | 0.75 | MET (0.37) | METNQO2DYRK1AJAK2TGFBR1 | |
| SCHEMBL20004070 | 0.74 | MET (0.41) | METNQO2DYRK1AJAK2TGFBR1 | |
| SCHEMBL25836231 | 0.73 | MET (0.38) | METNQO2DYRK1AJAK2TGFBR1 | |
| SCHEMBL29315243 | 0.71 | MET (0.34) | METNQO2DYRK1AJAK2PIK3CA | |
| SCHEMBL29315132 | 0.70 | DYRK1A (0.34) | DYRK1AJAK2TGFBR1PIK3CA | |
| SCHEMBL29316180 | 0.70 | KEAP1 (0.37) | METDYRK1A | |
| SCHEMBL22109398 | 0.69 | MERTK (0.39) | METDYRK1ATGFBR1 | |
| SCHEMBL29315788 | 0.69 | MET (0.40) | METNQO2DYRK1AJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |