Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12507042 | 0.86 | MAPT (0.49) | THRBLMNAEPHX2SMN1; SMN2 | |
| SCHEMBL10282539 | 0.86 | ALDH1A1 (0.67) | ACHEALDH1A1NPC1LMNARAB9A | |
| SCHEMBL24480908 | 0.84 | NPC1 (0.63) | ACHEALDH1A1NPC1THRBLMNA | |
| SCHEMBL25701777 | 0.83 | HSD11B1 (0.53) | ALDH1A1EPHX2SMN1; SMN2CACNA2D1CACNA1B | |
| SCHEMBL18909221 | 0.83 | GNAI3 (0.47) | ALDH1A1EPHX2EPHX1CACNA2D1CACNA1B | |
| SCHEMBL17285913 | 0.83 | ACHE (0.56) | ACHEALDH1A1NPC1THRBLMNA | |
| SCHEMBL24480964 | 0.83 | EPHX2 (0.40) | THRBEPHX2EPHX1SMN1; SMN2CACNA2D1 | |
| SCHEMBL25667319 | 0.83 | KDM4E (0.44) | ALDH1A1THRBLMNAEPHX2EPHX1 | |
| SCHEMBL20471042 | 0.82 | HRH3 (0.48) | ALDH1A1EPHX2SMN1; SMN2CACNA2D1CACNA1B | |
| SCHEMBL18909449 | 0.82 | CACNA2D1 (0.45) | ALDH1A1EPHX2EPHX1CACNA2D1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |