Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25027108 | 0.89 | ACHE (0.38) | ACHEGBA1KDM4EPOLB | |
| SCHEMBL25026643 | 0.86 | GBA1 (0.32) | GBA1CACNA2D1CACNA1BCACNB1MEN1 | |
| SCHEMBL25856192 | 0.85 | CYP1A2 (0.41) | GBA1 | |
| SCHEMBL25027129 | 0.85 | ACHE (0.53) | ACHEGBA1KDM4EPOLBCACNA2D1 | |
| SCHEMBL25856386 | 0.81 | ACHE (0.38) | ACHEGBA1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL25856391 | 0.80 | MEN1 (0.33) | MEN1ALDH1A1CYP2C9TSHRCYP2C19 | |
| SCHEMBL29317185 | 0.79 | ACHE (0.44) | ACHEGBA1KDM4EPOLBCACNA2D1 | |
| SCHEMBL24480318 | 0.79 | GNAO1 (0.35) | ACHEGBA1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL13661595 | 0.78 | ACHE (0.64) | ACHEGBA1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL24481344 | 0.77 | GBA1 (0.37) | ACHEGBA1CACNA2D1CACNA1BCACNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |