SCHEMBL29323153

SCHEMBL29323153

C[C@@H](COCCNC(=O)OC(C)(C)C)CN1C(=O)c2ccccc2C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 1/20 0.47
IDO1 P14902 1/20 0.42
BRD4 O60885 1/20 0.41
BCHE P06276 1/20 0.41
CNR2 P34972 1/20 0.41
PDK2 Q15119 1/20 0.41
ADRB2 P07550 2/20 0.41
HTR1A P08908 2/20 0.41
KCNA5 P22460 1/20 0.41
TPSAB1 Q15661 1/20 0.41
TPSD1 Q9BZJ3 1/20 0.41
TPSG1 Q9NRR2 1/20 0.41
LMNA P02545 1/20 0.40
PKM P14618 1/20 0.40
DDB1 Q16531 2/20 0.40
CRBN Q96SW2 2/20 0.40
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
MAPK1 P28482 1/20 0.39
NAMPT P43490 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18085408 0.84 MALT1 (0.49) MALT1BRD4KCNA5TPSAB1TPSD1
SCHEMBL21361609 0.83 MALT1 (0.47) MALT1BRD4KCNA5TPSAB1TPSD1
SCHEMBL21359217 0.83 MALT1 (0.47) MALT1BRD4KCNA5TPSAB1TPSD1
SCHEMBL18085398 0.83 MALT1 (0.47) MALT1BRD4KCNA5TPSAB1TPSD1
SCHEMBL30135170 0.83 MALT1 (0.47) MALT1BRD4KCNA5TPSAB1TPSD1
SCHEMBL9941674 0.83 MALT1 (0.50) MALT1IDO1BRD4BCHEPDK2
SCHEMBL29323224 0.83 LMNA (0.58) KCNA5TPSAB1TPSD1TPSG1LMNA
SCHEMBL4392860 0.82 MALT1 (0.49) MALT1IDO1BRD4BCHECNR2
SCHEMBL31072520 0.80 SYK (0.55) MALT1IDO1BCHECNR2TPSAB1
SCHEMBL8187243 0.80 MALT1 (0.47) MALT1IDO1BCHECNR2PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239771-A1 BACTERIAL EFFLUX PUMP INHIBITORS TAXIS PHARMACEUTICALS, INC. 2024-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239771-A1 BACTERIAL EFFLUX PUMP INHIBITORS ABCB11, ABCB1, SLC47A1 MALT1 3856/4885IDO1 2754/4885BRD4 3487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.