Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 5/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 5/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18085395 | 0.87 | CYP3A4 (0.53) | LMNASMN1; SMN2L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL31072561 | 0.86 | LMNA (0.57) | LMNASMN1; SMN2L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL29323153 | 0.83 | MALT1 (0.47) | LMNAMAPK1TPSAB1TPSD1TPSG1 | |
| SCHEMBL29262775 | 0.82 | LMNA (0.71) | LMNASMN1; SMN2L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL29323231 | 0.82 | SMN1; SMN2 (0.70) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL29323035 | 0.81 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL19016323 | 0.81 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL31072520 | 0.81 | SYK (0.55) | LMNASMN1; SMN2L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL2564693 | 0.78 | LMNA (0.64) | LMNASMN1; SMN2L3MBTL1HTTTPSAB1 | |
| SCHEMBL22151127 | 0.77 | RAB9A (0.64) | MAPK1CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239771-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | TAXIS PHARMACEUTICALS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239771-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | ABCB11, ABCB1, SLC47A1 | LMNA 3705/4885SMN1; SMN2 4880/4885L3MBTL1 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.