SCHEMBL29323600

SCHEMBL29323600

CCOC(=O)Cc1noc2ccc3c(C#CCOC4CCN(C(=O)OC(C)(C)C)CC4)cccc3c12

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 9/20 0.38
TP53 P04637 1/20 0.37
POLB P06746 1/20 0.37
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
MAPT P10636 1/20 0.35
CETP P11597 1/20 0.35
ALOX15 P16050 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 2/20 0.34
THRB P10828 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323602 0.79 DDB1 (0.46) GPR119CETP
SCHEMBL29323432 0.72 DDB1 (0.45) GPR119CETP
SCHEMBL30734613 0.71 GPR119 (0.44) GPR119TP53PDE4APDE4BPDE4C
SCHEMBL26636386 0.71 GPR119 (0.44) GPR119TP53PDE4APDE4BPDE4C
SCHEMBL29324722 0.70 GPR119 (0.39) GPR119PDE4APDE4BPDE4CPDE4D
SCHEMBL29322666 0.70 POLB (0.41) TP53POLBMAPTL3MBTL1LMNA
SCHEMBL24508322 0.69 DDB1 (0.48) GPR119
SCHEMBL29324846 0.68 KDM4E (0.49) GPR119TP53MAPTL3MBTL1LMNA
SCHEMBL31331074 0.66 ALOX5AP (0.41) TP53POLBL3MBTL1
SCHEMBL29324249 0.66 TP53 (0.38) GPR119TP53POLBMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed