SCHEMBL29324846

SCHEMBL29324846

CCOC(=O)Cc1noc2c(CC(=O)NC3CCN(C(=O)OC(C)(C)C)CC3)cccc12

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
KMT2A Q03164 3/20 0.46
LMNA P02545 2/20 0.46
MEN1 O00255 2/20 0.46
THRB P10828 1/20 0.46
MAPT P10636 1/20 0.46
GPR119 Q8TDV5 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
RAB9A P51151 1/20 0.43
USP2 O75604 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TP53 P04637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
HDAC4 P56524 1/20 0.41
ALDH1A1 P00352 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324509 0.81 TLR8 (0.42) KMT2AL3MBTL1
SCHEMBL29324249 0.79 TP53 (0.38) KDM4EKMT2ALMNAMEN1THRB
SCHEMBL31323712 0.79 CYP11B2 (0.47) LMNAMAPTGPR119SMN1; SMN2ALDH1A1
SCHEMBL31331074 0.78 ALOX5AP (0.41) TP53L3MBTL1
SCHEMBL29324845 0.75 MAPK8 (0.45) KDM4EKMT2AMEN1GPR119RAB9A
SCHEMBL25604356 0.74 ESR2 (0.39) KMT2ALMNAMEN1THRBGPR119
SCHEMBL7243177 0.73 DRD2 (0.47) KDM4EKMT2AMEN1MAPTGPR119
SCHEMBL7243170 0.73 GPR119 (0.47) KDM4EKMT2AMEN1MAPTGPR119
SCHEMBL25825902 0.72 L3MBTL1 (0.39) KMT2ALMNAMEN1GPR119SMN1; SMN2
SCHEMBL25604199 0.72 ESR2 (0.43) LMNAMAPTSMN1; SMN2L3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed