Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324248 | 0.90 | SMN1; SMN2 (0.41) | LMNATHRBGPR119TGFBR1KDM4E | |
| SCHEMBL29324151 | 0.85 | L3MBTL1 (0.41) | TP53POLBGPR119RAB9ATGFBR1 | |
| SCHEMBL29324846 | 0.79 | KDM4E (0.49) | TP53LMNATHRBMAPTGPR119 | |
| SCHEMBL29321732 | 0.78 | SMN1; SMN2 (0.44) | TP53POLBMAPTRAB9AL3MBTL1 | |
| SCHEMBL29324252 | 0.76 | DDB1 (0.47) | GPR119HDAC4 | |
| SCHEMBL31331074 | 0.75 | ALOX5AP (0.41) | TP53POLBL3MBTL1 | |
| SCHEMBL29324244 | 0.75 | TGFBR1 (0.41) | THRBMAPTGPR119RAB9ATGFBR1 | |
| SCHEMBL31323712 | 0.74 | CYP11B2 (0.47) | LMNAMAPTGPR119L3MBTL1ALDH1A1 | |
| SCHEMBL29324509 | 0.73 | TLR8 (0.42) | L3MBTL1KMT2A | |
| SCHEMBL25604356 | 0.72 | ESR2 (0.39) | TP53LMNAPOLBTHRBGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400499-A1 | GLUTARIMIDE COMPOUND AND USE THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |