SCHEMBL29323772

SCHEMBL29323772

C=Cc1ccc(C(=O)OCCS(=O)(=O)c2ccc(C(C)=O)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
HTT P42858 2/20 0.39
KMT2A Q03164 3/20 0.38
CA2 P00918 2/20 0.37
CA9 Q16790 1/20 0.37
MAPT P10636 1/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
CA1 P00915 1/20 0.36
HPGD P15428 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323767 0.87 KMT2A (0.44) ALDH1A1TDP1KMT2ACA2CA9
SCHEMBL29323769 0.87 TDP1 (0.44) ALDH1A1TDP1CA9MAPTLMNA
SCHEMBL29323762 0.85 SNCA (0.50) ALDH1A1TDP1L3MBTL1KMT2AMAPT
SCHEMBL29323779 0.82 TSHR (0.43) ALDH1A1TDP1CA2MAPTLMNA
SCHEMBL12376769 0.79 TDP1 (0.43) ALDH1A1TDP1L3MBTL1CA2LMNA
SCHEMBL14578755 0.78 KMT2A (0.57) ALDH1A1KMT2ACA2CA9MAPT
SCHEMBL26417020 0.77 SNCA (0.49) ALDH1A1TDP1KMT2ACA2CA9
SCHEMBL29323796 0.75 ALDH1A1 (0.49) ALDH1A1TDP1KMT2AMAPTMEN1
SCHEMBL4904335 0.74 ALDH1A1 (0.64) ALDH1A1TDP1KMT2ACA2CA9
SCHEMBL29110130 0.74 SNCA (0.48) ALDH1A1TDP1L3MBTL1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed